Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 10/20 | 0.64 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.60 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.60 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831536 | 0.95 | PIK3CG (0.70) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL2833123 | 0.94 | PIK3CG (0.71) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL16882665 | 0.85 | PIK3CG (0.73) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL2837166 | 0.83 | PIK3CG (0.74) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL2833524 | 0.81 | PIK3CG (0.67) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL2833057 | 0.79 | MEN1 (0.63) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL2832349 | 0.79 | PI4KB (0.64) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL4534987 | 0.78 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL3513224 | 0.78 | PIK3CG (0.70) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL5960477 | 0.77 | PIK3CG (0.73) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888546-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006125805-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2006-11-30 | — | — | WO | disclosed |