Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25868191 | 0.94 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL3222619 | 0.93 | CYSLTR2 (0.50) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL26667665 | 0.90 | HPGD (0.54) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL16362200 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL8361618 | 0.85 | CA12 (0.44) | NPC1RAB9AMEN1KMT2ACYP1A2 | |
| SCHEMBL27973236 | 0.85 | TDP1 (0.52) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL12441017 | 0.83 | L3MBTL1 (0.54) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL13321711 | 0.83 | DRD4 (0.44) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL15218757 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL12441036 | 0.83 | CYP1A2 (0.42) | SMN1; SMN2LMNANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116726997-A | Preparation method of amino acid functionalized column [5] aromatic hydrocarbon supermolecule chiral catalyst | 广西大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-116726997-A | Preparation method of amino acid functionalized column [5] aromatic hydrocarbon supermolecule chiral catalyst | 广西大学 | 2023-09-12 | — | — | CN | disclosed |
| EP-1959959-A2 | MORPHOLINE CARBOXAMIDE PROKINETICIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007067511-A2 | MORPHOLINE CARBOXAMIDE PROKINETICIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2007-06-14 | — | — | WO | disclosed |