SCHEMBL49667

SCHEMBL49667

Oc1ccc2cc(Br)ccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.56
CYP2A6 P11509 1/20 0.56
ALOX15 P16050 3/20 0.52
ESR1 P03372 8/20 0.52
ESR2 Q92731 8/20 0.52
CYP3A4 P08684 2/20 0.52
TSHR P16473 1/20 0.52
HIF1A Q16665 1/20 0.52
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 1/20 0.52
ALDH1A1 P00352 1/20 0.52
MAPT P10636 1/20 0.52
KMT2A Q03164 1/20 0.52
ABL1 P00519 1/20 0.48
ABCB1 P08183 1/20 0.48
BCR P11274 1/20 0.48
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30060950 1.00 CYP1A2 (0.56) CYP1A2CYP2A6ALOX15ESR1ESR2
SCHEMBL5280499 1.00 CYP1A2 (0.56) CYP1A2CYP2A6ALOX15ESR1ESR2
Potassium SCHEMBL31249479 0.97 CYP1A2 (0.54) CYP1A2CYP2A6ALOX15ESR1ESR2
Methane SCHEMBL10835252 0.97 CYP1A2 (0.54) CYP1A2CYP2A6ALOX15ESR1ESR2
Potassium SCHEMBL31249478 0.97 CYP1A2 (0.54) CYP1A2CYP2A6ALOX15ESR1ESR2
SCHEMBL11136750 0.95 CYP1A2 (0.52) CYP1A2CYP2A6ALOX15ESR1ESR2
SCHEMBL534661 0.92 CYP1A2 (0.54) CYP1A2CYP2A6ALOX15ESR1ESR2
SCHEMBL30970426 0.92 CYP1A2 (0.54) CYP1A2CYP2A6ALOX15ESR1ESR2
SCHEMBL31398211 0.92 CYP1A2 (0.54) CYP1A2CYP2A6ALOX15ESR1ESR2
Methoxymethane SCHEMBL27914657 0.91 ABL1 (0.48) CYP1A2CYP2A6ALOX15ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2708 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117229146-B Caffeic acid phenethyl ester derivative and preparation method and application thereof 中国药科大学 2025-06-17 CN claimed
EP-3494396-B1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY INC (US) 2025-06-11 EP claimed
CN-119930413-A Preparation method of nabumetone-D3 山东辉璟生物医药科技有限公司 2025-05-06 CN claimed
CN-119841715-A Method for directly preparing aromatic ether compound from aromatic aldehyde, ketone and phenol 湖南第一师范学院 2025-04-18 CN claimed
CN-119613438-A Dinaphthoboroxine structural derivative and preparation method and application thereof 西安欧得光电材料有限公司 2025-03-14 CN claimed
CN-119177106-A High-strength flame-retardant ultraviolet light curing adhesive and preparation process thereof 江西优科工业材料有限公司 2024-12-24 CN claimed
CN-119162735-A Preparation method and application of flexible fluorescent sensing film based on fluorescent probe 西安工程大学 2024-12-20 CN claimed
CN-118993947-A Preparation method of 6-amidine-2-naphthol methanesulfonic acid 荆楚理工学院 2024-11-22 CN claimed
CN-118834119-A Method for synthesizing bisphenol compound by catalysis of supported ionic liquid 郑州中科新兴产业技术研究院 2024-10-25 CN claimed
CN-113999089-B Method for synthesizing 6,6 '-dibromo-1, 1' -bi-2-naphthol by oxidative coupling of 6-bromo-2-naphthol 中唯炼焦技术国家工程研究中心有限责任公司 2024-05-14 CN claimed
US-4950588-A DETECTION OF NUCLEIC ACID HYBRIDS, ANTIBODIES ANTIGENS MOLECULAR DIAGNOSTICS, INC. (US) 1990-08-21 US claimed
WO-1990006372-A1 SUBSTRATES FOR PEROXIDASE ASSAYING MICROPROBE CORPORATION (US) 1990-06-14 WO claimed
US-4657993-A PREPARED FROM DICHLOROPHOSPHAZENES CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1987-04-14 US claimed
EP-0200854-A2 Phosphazene homopolymers and copolymers having hydroxylated or amino derivatives of carbazole or of naphthalene as substituents CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1986-12-17 EP claimed
US-4588833-A CARBON MONOXIDE, ALCOHOL OR AMINE, ACID, UNSATURATED AMIDE, COBALTCOMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1986-05-13 US claimed
US-4560744-A FOR NYLON AND NATURAL POLYAMIDES BASF AKTIENGESELLSCHAFT (DE) 1985-12-24 US claimed
EP-0116454-A2 Enhanced luminescent or luminometric assay NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-08-22 EP claimed
US-4374262-A Preparation of hydroxy aromatic carboxylic acids and ester derivatives thereof CELANESE CORPORATION (US) 1983-02-15 US claimed
EP-0049616-A1 Preparation of hydroxy aromatic carboxylic acids and ester derivatives thereof CELANESE CORPORATION (US) 1982-04-14 EP claimed
US-4137272-A Process for the manufacture of 2-alkoxy-6-bromo-naphthalenes HOECHST AKTIENGESELLSCHAFT (DE) 1979-01-30 US claimed