SCHEMBL5280499

SCHEMBL5280499

Oc1ccc2cc(Br)ccc2c1.Oc1ccc2cc(Br)ccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.56
CYP2A6 P11509 1/20 0.56
ALOX15 P16050 3/20 0.52
ESR1 P03372 8/20 0.52
ESR2 Q92731 8/20 0.52
CYP3A4 P08684 2/20 0.52
TSHR P16473 1/20 0.52
HIF1A Q16665 1/20 0.52
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 1/20 0.52
ALDH1A1 P00352 1/20 0.52
MAPT P10636 1/20 0.52
KMT2A Q03164 1/20 0.52
ABL1 P00519 1/20 0.48
ABCB1 P08183 1/20 0.48
BCR P11274 1/20 0.48
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49667 1.00 CYP1A2 (0.56) CYP1A2CYP2A6ALOX15ESR1ESR2
SCHEMBL30060950 1.00 CYP1A2 (0.56) CYP1A2CYP2A6ALOX15ESR1ESR2
Potassium SCHEMBL31249479 0.97 CYP1A2 (0.54) CYP1A2CYP2A6ALOX15ESR1ESR2
Methane SCHEMBL10835252 0.97 CYP1A2 (0.54) CYP1A2CYP2A6ALOX15ESR1ESR2
Potassium SCHEMBL31249478 0.97 CYP1A2 (0.54) CYP1A2CYP2A6ALOX15ESR1ESR2
SCHEMBL11136750 0.95 CYP1A2 (0.52) CYP1A2CYP2A6ALOX15ESR1ESR2
SCHEMBL534661 0.92 CYP1A2 (0.54) CYP1A2CYP2A6ALOX15ESR1ESR2
SCHEMBL30970426 0.92 CYP1A2 (0.54) CYP1A2CYP2A6ALOX15ESR1ESR2
SCHEMBL31398211 0.92 CYP1A2 (0.54) CYP1A2CYP2A6ALOX15ESR1ESR2
Methoxymethane SCHEMBL27914657 0.91 ABL1 (0.48) CYP1A2CYP2A6ALOX15ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007000329-A2 EPOXIDATION OF ALPHA, BETA-UNSATURATED KETONES LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-01-04 WO disclosed
EP-0938488-A1 PHOSPHINE LIGANDS OXFORD ASYMMETRY INTERNATIONAL PLC (GB) 1999-09-01 EP disclosed
WO-1998012202-A1 PHOSPHINE LIGANDS OXFORD ASYMMETRY INTERNATIONAL PLC. (GB) 1998-03-26 WO disclosed