Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4211040 | 0.92 | THRB (0.47) | THRBTHRA | |
| SCHEMBL4962808 | 0.91 | THRB (0.47) | THRBTHRA | |
| SCHEMBL3153304 | 0.89 | THRB (0.49) | THRBTHRA | |
| SCHEMBL4210588 | 0.87 | THRB (0.47) | THRBTHRA | |
| SCHEMBL4201342 | 0.86 | THRB (0.42) | THRBTHRA | |
| SCHEMBL4963977 | 0.84 | THRB (0.43) | THRBTHRA | |
| SCHEMBL1457675 | 0.84 | THRB (0.45) | THRBTHRA | |
| SCHEMBL4215714 | 0.83 | THRB (0.43) | THRBTHRA | |
| SCHEMBL3155979 | 0.83 | THRB (0.47) | THRBTHRA | |
| SCHEMBL3160054 | 0.82 | THRB (0.71) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890768-A2 | NOVEL PHOSPHINIC ACID-CONTAINING THYROMIMETICS | Metabasis Therapeutics, Inc. (US) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006128056-A2 | NOVEL PHOSPHINIC ACID-CONTAINING THYROMIMETICS | METABASIS THERAPEUTICS, INC. (US) | 2006-11-30 | — | — | WO | disclosed |