SCHEMBL4967294

SCHEMBL4967294

NCC1CCCC1CN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2484460 0.92 EPHX1 (0.36)
SCHEMBL727317 0.92 EPHX1 (0.36)
SCHEMBL277533 0.92 EPHX1 (0.36)
SCHEMBL18428581 0.92 EPHX1 (0.36)
Hydrochloric Acid SCHEMBL25267551 0.89 KDM4E (0.36)
SCHEMBL5414023 0.89 EPHX1 (0.41)
SCHEMBL8353641 0.89 EPHX1 (0.41)
SCHEMBL23803095 0.89 EPHX1 (0.35)
Hydrochloric Acid SCHEMBL7214950 0.85 CA1 (0.31)
SCHEMBL3538822 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8865149-B2 Polymeric reagents comprising a ketone or a related functional group NEKTAR THERAPEUTICS (US) 2014-10-21 US disclosed
US-8865149-B2 Polymeric reagents comprising a ketone or a related functional group NEKTAR THERAPEUTICS (US) 2014-10-21 US disclosed
US-8835556-B2 Hydrolytically stable maleimide-terminated polymers NEKTAR THERAPEUTICS (US) 2014-09-16 US disclosed
US-20120226022-A1 HYDROLYTICALLY STABLE MALEIMIDE-TERMINATED POLYMERS NEKTAR THERAPEUTICS (US) 2012-09-06 US disclosed
US-8227555-B2 Hydrolytically stable maleimide-terminated polymers NEKTAR THERAPEUTICS (US) 2012-07-24 US disclosed
US-20120123065-A1 Hydrolytically Stable Maleimide-Terminated Polymers NEKTAR THERAPEUTICS (US) 2012-05-17 US disclosed
US-8106131-B2 Hydrolytically stable maleimide-terminated polymers NEKTAR THERAPEUTICS (US) 2012-01-31 US disclosed
EP-1578842-B1 HYDROLYTICALLY STABLE MALEIMIDE-TERMINATED POLYMERS NEKTAR THERAPEUTICS AL CORP (US) 2009-10-07 EP disclosed
US-20090012241-A1 Hydrolytically stable maleimide-terminated polymers NEKTAR THERAPEUTICS AL, CORPORATION (US) 2009-01-08 US disclosed
US-7432331-B2 Hydrolytically stable maleimide-terminated polymers NEKTAR THERAPEUTICS AL, CORPORATION (US) 2008-10-07 US disclosed
US-7432330-B2 Hydrolytically stable maleimide-terminated polymers NEKTAR THERAPEUTICS AL, CORPORATION (US) 2008-10-07 US disclosed
US-20070166277-A1 Polymeric reagents comprising a ketone or a related functional group NEKTAR THERAPEUTICS 2007-07-19 US disclosed
US-20070166277-A1 Polymeric reagents comprising a ketone or a related functional group NEKTAR THERAPEUTICS 2007-07-19 US disclosed
US-7208145-B2 Useful for providing conjugates with other substances NEKTAR THERAPEUTICS AL, CORPORATION (US) 2007-04-24 US disclosed
US-7208145-B2 Useful for providing conjugates with other substances NEKTAR THERAPEUTICS AL, CORPORATION (US) 2007-04-24 US disclosed
US-6008395-A REACTING A PLATINUM COMPLEX WHICH CONTAINS A HALOGEN ATOM ATTACHED WITH PLATINUM WITH SILVER SALT OF C2-C8 ALKYL MONOCARBOXYLIC ACID TO PRODUCE DIHALIDE CONTAINING PLATINUM COMPLEX; ANTICARCINOGENIC AGENT YUKI KIDANI, SOLE HEIR (GB) 1999-12-28 US disclosed
EP-0812852-A1 NOVEL PLATINUM (IV) COMPLEXES, PROCESS FOR PRODUCING THE SAME, AND CARCINOSTATIC AGENTS CONTAINING THE SAME Kidani, Yoshinori (JP) 1997-12-17 EP disclosed