SCHEMBL2484460

SCHEMBL2484460

NC[C@H]1CCCC[C@@H]1CN

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.36
THRB P10828 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
GABRR1 P24046 4/20 0.33
TP53 P04637 1/20 0.33
GABRR2 P28476 1/20 0.33
SIGMAR1 Q99720 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL277533 1.00 EPHX1 (0.36) EPHX1THRBMEN1KMT2AGABRR1
SCHEMBL18428581 1.00 EPHX1 (0.36) EPHX1THRBMEN1KMT2AGABRR1
SCHEMBL727317 1.00 EPHX1 (0.36) EPHX1THRBMEN1KMT2AGABRR1
SCHEMBL8353641 0.96 EPHX1 (0.41) EPHX1THRBMEN1KMT2ATP53
SCHEMBL5414023 0.96 EPHX1 (0.41) EPHX1THRBMEN1KMT2ATP53
SCHEMBL23803095 0.96 EPHX1 (0.35) EPHX1THRBMEN1KMT2AGABRR1
Hydrochloric Acid SCHEMBL25267551 0.96 KDM4E (0.36) EPHX1THRBMEN1KMT2AGABRR1
SCHEMBL4967294 0.92
SCHEMBL21034603 0.87 SIGMAR1 (0.37) EPHX1SIGMAR1
SCHEMBL14672056 0.85 TDP1 (0.41) GABRR1TP53GABRR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114854196-B Polyimide film 株式会社斗山 2024-05-28 CN disclosed
CN-115298248-B Polyimide film having moisture absorption resistance and water absorption resistance 株式会社斗山 2024-03-08 CN disclosed
US-20240034838-A1 POLYAMIC ACID RESIN AND POLYIMIDE FILM USING THE SAME DOOSAN CORPORATION (KR) 2024-02-01 US disclosed
CN-117430808-A Polyamic acid resin and transparent polyimide film using same 株式会社斗山 2024-01-23 CN disclosed
EP-3133108-B1 FIBER-REINFORCED COMPOSITE MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2023-08-02 EP disclosed
CN-115011116-A Polyimide film 株式会社斗山 2022-09-06 CN disclosed
CN-114854196-A Polyimide film 株式会社斗山 2022-08-05 CN disclosed
CN-113260676-A Polyimide film having excellent weather resistance 株式会社斗山 2021-08-13 CN disclosed
CN-113260675-A Polyimide film having excellent yield strain and bending characteristics 株式会社斗山 2021-08-13 CN disclosed
WO-2021117960-A1 POLYIMIDE FILM HAVING EXCELLENT YIELD STRAIN AND FLEXURAL CHARACTERISTICS 주식회사 두산 2021-06-17 WO disclosed
US-20080176854-A1 Nitro-Substituted Phenyl-Piperazine Compounds, Their Preparation and Use in Medicaments LABORATORIOS DEL DR. ESTEVE S.A (ES) 2008-07-24 US disclosed
WO-2008034815-A1 COMBINATION OF NMDA- RECEPTOR LIGAND AND A COMPOUND WITH 5-HT6 RECEPTOR AFFINITY LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2008-03-27 WO disclosed
EP-1902733-A1 Combination of a NMDA-receptor ligand and a compound with 5-HT6 receptor affinity LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2008-03-26 EP disclosed
WO-2007147883-A1 COMBINATION OF A CHOLINESTERASE INHIBITOR AND A COMPOUND WITH 5-HT6 RECEPTOR AFFINITY LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-12-27 WO disclosed
EP-1851210-A2 NITRO-SUBSTITUTED PHENYL-PIPERAZINE COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-11-07 EP disclosed
EP-1844031-A1 SUBSTITUTED PHENYL-PIPERAZINE COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-10-17 EP disclosed
EP-1695971-A1 Substituted phenyl-piperazine compounds, their preparation and use in medicaments LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2006-08-30 EP disclosed
WO-2006069807-A1 SUBSTITUTED PHENYL-PIPERAZINE COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2006-07-06 WO disclosed
WO-2006069808-A2 NITRO-SUBSTITUTED PHENYL-PIPERAZINE COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2006-07-06 WO disclosed
EP-1676842-A1 Nitro-substituted phenyl-piperazine compounds, their preparation and use in medicaments LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2006-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080176854-A1 Nitro-Substituted Phenyl-Piperazine Compounds, Their Preparation and Use in Medicaments HTR6, HTR5A, P2RX5 EPHX1 2849/4885THRB 2783/4885MEN1 3555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.