SCHEMBL4967897

SCHEMBL4967897

CO[Si](CCCCCCCCSC(C)=O)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.37
HDAC4 P56524 3/20 0.37
HDAC1 Q13547 3/20 0.37
HDAC2 Q92769 3/20 0.37
HDAC8 Q9BY41 3/20 0.37
HDAC6 Q9UBN7 3/20 0.37
HDAC7 Q8WUI4 2/20 0.37
HDAC10 Q969S8 2/20 0.37
HDAC11 Q96DB2 2/20 0.37
HDAC9 Q9UKV0 2/20 0.37
HDAC5 Q9UQL6 2/20 0.37
CYP2C19 P33261 1/20 0.36
POLB P06746 1/20 0.35
BLM P54132 1/20 0.35
ATM Q13315 1/20 0.35
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3682359 0.92 CYP2C19 (0.39) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL3656326 0.84 CYP2C19 (0.41) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL27646679 0.81 HDAC3 (0.36) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL28345659 0.81 HDAC3 (0.36) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL4971701 0.81 HDAC3 (0.36) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL6871500 0.78 CYP2C19 (0.52) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL14478080 0.78 CYP2C19 (0.52) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL30205681 0.78 LMNA (0.44) HDAC11LMNA
SCHEMBL30205733 0.78 LMNA (0.44) HDAC11LMNA
SCHEMBL30205645 0.78 LMNA (0.44) HDAC11LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113795499-B Process for producing alkoxysilyl group-containing thiocarboxylate 迈图高新材料公司 2024-03-19 CN claimed
CN-113795499-A Process for producing alkoxysilyl group-containing thiocarboxylic ester 迈图高新材料公司 2021-12-14 CN claimed
CN-100422192-C Method for producing blocked mercaptosilanes GEN ELECTRIC (US) 2008-10-01 CN claimed
CN-1784412-A Method for producing blocked mercaptosilanes GEN ELECTRIC (US) 2006-06-07 CN claimed
CN-1247687-C Mineral filled elastomeric compositions CROMPTON CORP (US) 2006-03-29 CN claimed
CN-1481419-A Mineral filled elastomeric compositions ��³�նٹ�˾ 2004-03-10 CN claimed
CN-113795499-B Process for producing alkoxysilyl group-containing thiocarboxylate 迈图高新材料公司 2024-03-19 CN disclosed
CN-113795499-A Process for producing alkoxysilyl group-containing thiocarboxylic ester 迈图高新材料公司 2021-12-14 CN disclosed
CN-105452261-B continuous process for preparing thiocarboxylate silane 莫门蒂夫性能材料股份有限公司 2019-12-10 CN disclosed
CN-105452261-A Continuous process for the preparation of thiocarboxylate silane MOMENTIVE PERFORMANCE MAT INC 2016-03-30 CN disclosed
EP-1270581-B1 Blocked mercaptosilane coupling agents for filled rubbers MOMENTIVE PERFORMANCE MAT INC (US) 2014-02-19 EP disclosed
CN-101880415-B Silica-rubber mixtures having improved hardness MOMENTIVE PERFORMANCE MAT INC (US) 2013-05-22 CN disclosed
CN-1681876-B Silica-rubber mixtures with improved hardness MOMENTIVE PERFORMANCE MAT INC (US) 2012-05-30 CN disclosed
US-20020099118-A1 For use in tires, shoe soles WITCO CORPORATION, A CORPORATION OF THE STATE OF DELAWARE 2002-07-25 US disclosed
US-6414061-B1 CURABLE MIXTURE CROMPTON CORPORATION 2002-07-02 US disclosed
US-20020055646-A1 Reacting a mercaptosilane and a monoacid anhydride corresponding to a thioester group present in the desired product, or reacting alkali salt of a mercaptosilane with an acid anhydride or acid halide or transesterification WITCO CORPORATION 2002-05-09 US disclosed
US-20020055568-A1 3-(acylmercapto)propyltrialkoxy- or trihydroxysilane WITCO CORPORATION 2002-05-09 US disclosed
US-20020055564-A1 Sulfur silane coupling agents which are latent WITCO CORPORATION 2002-05-09 US disclosed
EP-0958298-A1 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS WITCO CORPORATION (US) 1999-11-24 EP disclosed
WO-1999009036-A1 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS OSI SPECIALTIES, INC. (US) 1999-02-25 WO disclosed