SCHEMBL4968145

SCHEMBL4968145

O=C1C[C@H](O)C=C1CCCCCCCO

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.32
STAT3 P40763 1/20 0.32
CA2 P00918 1/20 0.31
TBXAS1 P24557 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11462482 1.00 DAO (0.32) DAOSTAT3CA2TBXAS1
SCHEMBL11196622 0.83 STAT3 (0.32) STAT3
SCHEMBL11195808 0.83 STAT3 (0.32) STAT3
SCHEMBL11193632 0.83 STAT3 (0.32) STAT3
SCHEMBL7621615 0.81 F13A1 (0.46) TBXAS1
SCHEMBL6036831 0.81 F13A1 (0.46) TBXAS1
SCHEMBL11688948 0.81 F13A1 (0.46) TBXAS1
SCHEMBL10626171 0.80 PPARG (0.35)
SCHEMBL11787951 0.77 HPGD (0.41) CA2
SCHEMBL2720980 0.77 HPGD (0.41) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0845534-B1 Esterase gene and its use SUMITOMO CHEMICAL CO (JP) 2008-06-25 EP disclosed
US-6960460-B2 Nucleotide sequences coding enzymatic polypeptide for use in the generation insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-11-01 US disclosed
US-6087145-A CODES FOR ENZYME CAPABLE OF ASYMMETRIC HYDROLYSIS OF ORGANIC CARBOXYLIC ACID ESTER OF A CYCLOPENTENOLONE; FOR RECOMBINANT PRODUCTION OF ENZYME TO PRODUCE OPTICALLY ACTIVE CHEMICAL INTERMEDIATES OF DRUGS AND AGRICULTURAL CHEMICALS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-07-11 US disclosed
EP-0845534-A2 Esterase gene and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-06-03 EP disclosed