Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967427 | 1.00 | HPGD (0.41) | HPGDPTGER2TSHRLMNAALDH1A1 | |
| SCHEMBL11787951 | 1.00 | HPGD (0.41) | HPGDPTGER2TSHRLMNAALDH1A1 | |
| SCHEMBL2677059 | 1.00 | HPGD (0.41) | HPGDPTGER2TSHRLMNAALDH1A1 | |
| SCHEMBL9497174 | 0.99 | TSHR (0.40) | HPGDPTGER2TSHRLMNAALDH1A1 | |
| SCHEMBL9496137 | 0.99 | TSHR (0.40) | HPGDPTGER2TSHRLMNAALDH1A1 | |
| SCHEMBL10753712 | 0.86 | CYP4F2 (0.44) | TSHRALDH1A1GAAKMT2AEPHX2 | |
| SCHEMBL9498988 | 0.86 | CYP4F2 (0.44) | TSHRALDH1A1GAAKMT2AEPHX2 | |
| SCHEMBL11810537 | 0.86 | CYP4F2 (0.44) | TSHRALDH1A1GAAKMT2AEPHX2 | |
| SCHEMBL9496265 | 0.86 | CYP4F2 (0.44) | TSHRALDH1A1GAAKMT2AEPHX2 | |
| SCHEMBL11808317 | 0.86 | CYP4F2 (0.44) | TSHRALDH1A1GAAKMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010603-A | Synthesis method of misoprostol intermediate | 深圳万乐药业有限公司 | 2022-09-06 | — | — | CN | claimed |
| US-5106750-A | Enzymatic resolution of hydroxycyclopentenones using lipase | G. D. SEARLE & CO. (US) | 1992-04-21 | — | — | US | claimed |
| JP-5041998-A | — | — | None | — | — | JP | disclosed |
| JP-63119439-A | — | — | None | — | — | JP | disclosed |
| CN-111148730-B | Process for the preparation and purification of misoprostol | 奇诺因药物和化学工厂私人有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-115010603-A | Synthesis method of misoprostol intermediate | 深圳万乐药业有限公司 | 2022-09-06 | — | — | CN | disclosed |
| US-20200330479-A1 | COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS USING NON-NATURALLY OCCURRING PROSTAGLANDINS | THE PROCTER & GAMBLE COMPANY | 2020-10-22 | — | — | US | disclosed |
| US-10759734-B2 | Process for the preparation and purification of misoprostol | CHINOIN PHARMACEUTICAL AND CHEMICAL WORKS PRIVATE COMPANY LTD. (HU) | 2020-09-01 | — | — | US | disclosed |
| US-20200165186-A1 | PROCESS FOR THE PREPARATION AND PURIFICATION OF MISOPROSTOL | CHINOIN PHARMACEUTICAL AND CHEMICAL WORKS PRIVATE CO. LTD. (HU) | 2020-05-28 | — | — | US | disclosed |
| CN-111148730-A | Process for the preparation and purification of misoprostol | 奇诺因药物和化学工厂私人有限公司 | 2020-05-12 | — | — | CN | disclosed |
| US-20190175475-A1 | COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS USING NON-NATURALLY OCCURRING PROSTAGLANDINS | THE PROCTER & GAMBLE COMPANY | 2019-06-13 | — | — | US | disclosed |
| US-4046801-A | 13-Cis prostaglandin derivatives | SYNTEX (U.S.A.) INC. (US) | 1977-09-06 | — | — | US | disclosed |
| US-4029698-A | Cycloalkylidenol analogues of prostaglandins E and F | MILES LABORATORIES, INC. (US) | 1977-06-14 | — | — | US | disclosed |
| US-4028396-A | BRONCHODILATORS, GASTRIC ACID SECRETION INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-3970683-A | 11,15-Dihydroxy-9-oxoprost-13-ynoic acid | G. D. SEARLE & CO. (US) | 1976-07-20 | — | — | US | disclosed |
| US-3969391-A | Preparation of prostaglandin precursors | G. D. SEARLE & CO. (US) | 1976-07-13 | — | — | US | disclosed |
| US-3965143-A | 16-Oxygenated prostanoic acid derivatives | G. D. SEARLE & CO. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3932479-A | BRONCHODILATOR, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1976-01-13 | — | — | US | disclosed |
| US-3931411-A | PROSTAGLANDINS | G. D. SEARLE & CO. (US) | 1976-01-06 | — | — | US | disclosed |
| JP-H00541998-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190175475-A1 | COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS USING NON-NATURALLY OCCURRING PROSTAGLANDINS | PTGES, PTGS1, PTGS2 | HPGD 12/4885PTGER2 11/4885TSHR 4378/4885 |
| US-10759734-B2 | Process for the preparation and purification of misoprostol | F12, VKORC1L1, SART3 | HPGD 302/4885PTGER2 71/4885TSHR 773/4885 |
| US-20200165186-A1 | PROCESS FOR THE PREPARATION AND PURIFICATION OF MISOPROSTOL | SART3, TBL3, TMSB4X | HPGD 1488/4885PTGER2 97/4885TSHR 70/4885 |
| US-20200330479-A1 | COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS USING NON-NATURALLY OCCURRING PROSTAGLANDINS | PTGES, PTGS1, PTGS2 | HPGD 12/4885PTGER2 11/4885TSHR 4378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.