Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.84 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 4/20 | 0.53 |
| ▸ | HTR1B | P28222 | 4/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4968803 | 0.91 | HTR6 (0.84) | HTR6HTR1DHTR1B | |
| SCHEMBL3153292 | 0.91 | HTR6 (1.00) | HTR6 | |
| SCHEMBL4977226 | 0.88 | HTR6 (0.75) | HTR6MPOHTR1DHTR1BHTR2A | |
| SCHEMBL3138888 | 0.84 | HTR6 (0.86) | HTR6MPOHTR2A | |
| SCHEMBL3147704 | 0.83 | HTR6 (1.00) | HTR6HTR1DHTR1BHTR2A | |
| SCHEMBL3147744 | 0.83 | HTR6 (1.00) | HTR6 | |
| SCHEMBL3324172 | 0.81 | HTR6 (0.82) | HTR6 | |
| SCHEMBL4969882 | 0.80 | HTR6 (0.76) | HTR6HTR1DHTR1BHTR2A | |
| SCHEMBL4967568 | 0.80 | HTR6 (0.70) | HTR6HTR1DHTR1BHTR2A | |
| SCHEMBL4970689 | 0.78 | HTR6 (0.83) | HTR6MPOHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626715-B1 | USE OF SULPHONAMIDE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE PROPHYLAXIS AND/OR TREATMENT OF DISORDERS OF FOOD INGESTION | ESTEVE LABOR DR (ES) | 2008-09-10 | — | — | EP | claimed |