Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.45 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.45 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.45 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.45 |
| ▸ | CBFB | Q13951 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11742502 | 0.81 | EPHX1 (0.47) | HTTSMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL11323733 | 0.81 | PKM (0.51) | HTTSMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL29426352 | 0.81 | PKM (0.51) | HTTSMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL7659979 | 0.80 | HTT (0.54) | HTTSMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL11772594 | 0.79 | TDP1 (0.53) | HTTSMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL6154023 | 0.79 | CA12 (0.45) | HTTMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL25519181 | 0.79 | KDM4E (0.55) | HTTSMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL8780994 | 0.77 | PKM (0.56) | HTTSMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL11639507 | 0.77 | RXFP1 (0.51) | HTTSMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL527724 | 0.77 | IDO1 (0.64) | HTTSMN1; SMN2L3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008101938-A1 | GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZONITRILE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-28 | — | — | WO | disclosed |
| WO-2008101938-A1 | GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZONITRILE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-28 | — | — | WO | disclosed |