SCHEMBL4968362

SCHEMBL4968362

CC(C)NC(=O)NCC(=O)N1CC(NC(=O)c2ccccc2)CC1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 7/20 0.53
ACE P12821 7/20 0.46
ANPEP P15144 4/20 0.44
AGTR2 P50052 4/20 0.43
DPP4 P27487 1/20 0.40
PREP P48147 1/20 0.40
FAP Q12884 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2399963 1.00 MMP2 (0.53) MMP2ACEANPEPAGTR2DPP4
SCHEMBL4967685 0.88 MMP2 (0.53) MMP2ACEANPEPAGTR2DPP4
SCHEMBL2399418 0.88 MMP2 (0.53) MMP2ACEANPEPAGTR2DPP4
SCHEMBL2527730 0.86 MMP2 (0.58) MMP2ACEANPEPAGTR2DPP4
SCHEMBL2401942 0.86 MMP2 (0.58) MMP2ACEANPEPAGTR2DPP4
SCHEMBL2399323 0.85 MMP2 (0.49) MMP2ACEANPEPAGTR2DPP4
SCHEMBL4969696 0.85 MMP2 (0.49) MMP2ACEANPEPAGTR2DPP4
SCHEMBL2399790 0.83 MMP2 (0.57) MMP2ACEANPEPAGTR2HPGD
SCHEMBL2526009 0.83 MMP2 (0.57) MMP2ACEANPEPAGTR2HPGD
SCHEMBL2398912 0.81 MMP2 (0.50) MMP2ACEANPEPAGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1966130-A2 MODIFIED LYSINE-MIMETIC COMPOUNDS Zealand Pharma A/S (DK) 2008-09-10 EP disclosed
WO-2007078990-A2 MODIFIED LYSINE-MIMETIC COMPOUNDS ZEALAND PHARMA A/S (DK) 2007-07-12 WO disclosed