Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DDIT3 | P35638 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440613 | 0.94 | KMT2A (0.44) | MEN1KMT2AABCG2CCR2ALDH1A1 | |
| SCHEMBL2425351 | 0.93 | MEN1 (0.49) | MEN1KMT2AABCG2CCR2ALDH1A1 | |
| SCHEMBL2421088 | 0.93 | KMT2A (0.48) | MEN1KMT2ACCR2ALDH1A1MAPK9 | |
| SCHEMBL2419313 | 0.90 | MEN1 (0.49) | MEN1KMT2AABCG2CCR2ALDH1A1 | |
| SCHEMBL7437813 | 0.88 | KMT2A (0.47) | MEN1KMT2ACCR2ALDH1A1MAPK9 | |
| SCHEMBL2423290 | 0.87 | KMT2A (0.48) | MEN1KMT2ACCR2ALDH1A1TGM2 | |
| SCHEMBL2419207 | 0.86 | MEN1 (0.46) | MEN1KMT2ACCR2MAPK9MAPK10 | |
| SCHEMBL2428331 | 0.86 | KMT2A (0.51) | MEN1KMT2ACCR2ALDH1A1MAPK9 | |
| SCHEMBL2419389 | 0.86 | KMT2A (0.50) | MEN1KMT2ACCR2ALDH1A1MAPK9 | |
| SCHEMBL2425516 | 0.85 | MEN1 (0.54) | MEN1KMT2ACCR2ALDH1A1MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904181-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011762-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2007-01-25 | — | — | WO | disclosed |