Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 19/20 | 0.93 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.93 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.93 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4095861 | 0.97 | CHRM3 (0.88) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL12725271 | 0.97 | CHRM3 (1.00) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL12725342 | 0.96 | CHRM3 (1.00) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL4099839 | 0.96 | CHRM3 (0.86) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL1631520 | 0.95 | CHRM3 (1.00) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL12725281 | 0.95 | CHRM3 (0.88) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL4106075 | 0.95 | CHRM3 (0.85) | CHRM3CHRM2CHRM1KCNH2 | |
| Trifluoroacetic Acid SCHEMBL1632285 | 0.95 | CHRM3 (0.85) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL4105534 | 0.95 | CHRM3 (1.00) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL12725299 | 0.94 | CHRM3 (1.00) | CHRM3CHRM2CHRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957075-A2 | NOVEL M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-08-20 | — | — | EP | claimed |
| WO-2006055553-A2 | NOVEL M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-05-26 | — | — | WO | claimed |
| US-7932247-B2 | M3 muscarinic acetylcholine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2011-04-26 | — | — | US | disclosed |
| US-7932247-B2 | M3 muscarinic acetylcholine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2011-04-26 | — | — | US | disclosed |
| US-20090149447-A1 | Novel M3 Muscarinic Acetylcholine Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2009-06-11 | — | — | US | disclosed |
| US-20090149447-A1 | Novel M3 Muscarinic Acetylcholine Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2009-06-11 | — | — | US | disclosed |
| EP-1957075-A2 | NOVEL M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-08-20 | — | — | EP | disclosed |
| WO-2006055553-A2 | NOVEL M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149447-A1 | Novel M3 Muscarinic Acetylcholine Receptor Antagonists | CHRM3, CHRM2, CHRNA3 | CHRM3 1/4885CHRM2 2/4885CHRM1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.