Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593124 | 1.00 | DPP4 (0.53) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL666318 | 0.81 | DPP4 (0.53) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL4603345 | 0.81 | DPP4 (0.53) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL666277 | 0.81 | DPP4 (0.54) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL195631 | 0.80 | DPP4 (0.54) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL29918628 | 0.80 | DPP4 (0.54) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2553750 | 0.80 | DPP4 (0.54) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL4603612 | 0.80 | DPP4 (0.55) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL666762 | 0.80 | DPP4 (0.55) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL663076 | 0.80 | DPP4 (0.61) | DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966193-A1 | NEW SALT AND POLYMORPH OF DPP-IV INHIBITOR | F. Hoffmann-la Roche AG (CH) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007071576-A1 | NEW SALT AND POLYMORPH OF DPP-IV INHIBITOR | F. HOFFMANN-LA ROCHE AG (CH) | 2007-06-28 | — | — | WO | disclosed |