Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 10/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18034957 | 0.81 | KMT2A (0.55) | FGFR1KCNH2KMT2AGAAHPGD | |
| SCHEMBL31202980 | 0.77 | NPC1 (0.50) | FGFR1KMT2AGAAHPGD | |
| SCHEMBL27618584 | 0.69 | CYP17A1 (0.35) | FGFR1KMT2AHPGD | |
| SCHEMBL620666 | 0.68 | HTT (0.53) | KMT2AGAA | |
| SCHEMBL1975997 | 0.68 | FGFR1 (0.54) | FGFR1KMT2AGAAHPGDGABRG2 | |
| Hydrochloric Acid SCHEMBL6327753 | 0.68 | CYP17A1 (0.34) | FGFR1KMT2AHPGD | |
| SCHEMBL29526031 | 0.68 | FGFR1 (0.42) | FGFR1KCNH2HPGD | |
| SCHEMBL8733535 | 0.67 | FGFR1 (0.53) | FGFR1KMT2AGAAHPGDGABRG2 | |
| SCHEMBL14344253 | 0.67 | MAPT (0.61) | KMT2A | |
| SCHEMBL14656406 | 0.65 | FGFR1 (0.52) | FGFR1KCNH2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910366-A2 | 1,4-DIHYDROPYRIDINE-FUSED HETEROCYCLES, PROCESS FOR PREPARING THE SAME, USE AND COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007012972-A2 | 1,4-DIHYDROPYRIDINE-FUSED HETEROCYCLES, PROCESS FOR PREPARING THE SAME, USE AND COMPOSITIONS CONTAINING THEM | AVENTIS PHARMA S.A. (FR) | 2007-02-01 | — | — | WO | disclosed |