Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.94 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.94 |
| ▸ | MAOA | P21397 | 1/20 | 0.73 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.64 |
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
| ▸ | MPO | P05164 | 2/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ADH1B | P00325 | 1/20 | 0.52 |
| ▸ | ADH1C | P00326 | 1/20 | 0.52 |
| ▸ | ADH1A | P07327 | 1/20 | 0.52 |
| ▸ | ADH7 | P40394 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764 | 0.97 | MEN1 (1.00) | MEN1KMT2ATDP1MAOACHRM2 | |
| Arsenic SCHEMBL28302928 | 0.94 | MEN1 (0.94) | MEN1KMT2ATDP1MAOACHRM2 | |
| Water SCHEMBL4230715 | 0.94 | MEN1 (0.94) | MEN1KMT2ATDP1MAOACHRM2 | |
| Ammonia Solution, Strong SCHEMBL6678345 | 0.94 | MEN1 (0.94) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL5040570 | 0.94 | MEN1 (0.94) | MEN1KMT2ATDP1MAOACHRM2 | |
| Ammonia Solution, Strong SCHEMBL28179631 | 0.94 | MEN1 (0.94) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL4922899 | 0.94 | MEN1 (0.94) | MEN1KMT2ATDP1MAOACHRM2 | |
| Hydrochloric Acid SCHEMBL5845845 | 0.94 | MEN1 (0.94) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL4913828 | 0.94 | MEN1 (0.94) | MEN1KMT2ATDP1MAOACHRM2 | |
| Hydrochloric Acid SCHEMBL11324591 | 0.94 | MEN1 (0.94) | MEN1KMT2ATDP1MAOACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507628-A | Novel benzodiazepine compound, preparation method and application thereof | 中国药科大学 | 2023-07-28 | — | — | CN | claimed |
| US-4061676-A | Recovery of doxycycline and products thereof | VILLAX IVAN | 1977-12-06 | — | — | US | claimed |
| EP-1954260-A2 | ISOCYSTENE DERIVATIVES FOR THE TREATMENT OF PAIN | Pfizer Limited (GB) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007057756-A2 | ISOCYSTENE DERIVATIVES FOR THE TREATMENT OF PAIN | PFIZER LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |
| US-5120728-A | CEPHALOSPORIN COMPOUNDS | PFIZER INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0420543-A2 | Cephalosporin compounds | PFIZER INC. (US) | 1991-04-03 | — | — | EP | disclosed |
| EP-0128718-A1 | Process for 6-(aminomethyl)penicillanic acid 1,1-dioxide and derivatives thereof | PFIZER INC. (US) | 1984-12-19 | — | — | EP | disclosed |