Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.94 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.94 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | MAOA | P21397 | 1/20 | 0.73 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.64 |
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ADH1B | P00325 | 1/20 | 0.52 |
| ▸ | ADH1C | P00326 | 1/20 | 0.52 |
| ▸ | ADH1A | P07327 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11324591 | 1.00 | MEN1 (0.94) | MEN1KMT2ATDP1MAPTGAA | |
| SCHEMBL5764 | 0.97 | MEN1 (1.00) | MEN1KMT2ATDP1MAPTGAA | |
| Arsenic SCHEMBL28302928 | 0.94 | MEN1 (0.94) | MEN1KMT2ATDP1MAPTGAA | |
| Water SCHEMBL4230715 | 0.94 | MEN1 (0.94) | MEN1KMT2ATDP1MAPTGAA | |
| Ammonia Solution, Strong SCHEMBL6678345 | 0.94 | MEN1 (0.94) | MEN1KMT2ATDP1MAPTGAA | |
| SCHEMBL4913828 | 0.94 | MEN1 (0.94) | MEN1KMT2ATDP1MAPTGAA | |
| SCHEMBL5040570 | 0.94 | MEN1 (0.94) | MEN1KMT2ATDP1MAPTGAA | |
| SCHEMBL4922899 | 0.94 | MEN1 (0.94) | MEN1KMT2ATDP1MAPTGAA | |
| Ammonia Solution, Strong SCHEMBL28179631 | 0.94 | MEN1 (0.94) | MEN1KMT2ATDP1MAPTGAA | |
| SCHEMBL4969293 | 0.94 | MEN1 (0.94) | MEN1KMT2ATDP1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651403-B | Synthesis method of cefoxitin sodium | 上海上药新亚药业有限公司 | 2022-01-07 | — | — | CN | claimed |
| CN-108752216-B | Green preparation method of high-purity N, N' -dibenzyl ethylenediamine diacetic acid | 重庆天地药业有限责任公司 | 2021-07-16 | — | — | CN | claimed |
| US-7071329-B2 | Process for preparing cephalosporins with salified intermediate | ACS DOBFAR S.P.A. (IT) | 2006-07-04 | — | — | US | claimed |
| US-20050119244-A1 | Process for preparing cephalosporins with salified intermediate | ACS DOBFAR S.P.A. (IT) | 2005-06-02 | — | — | US | claimed |
| US-20050119478-A1 | Process for preparing cephalosporins with salified intermediate | ACS DOBFAR S.P.A. (IT) | 2005-06-02 | — | — | US | claimed |
| CN-116283600-A | Recovery method and application of N, N-benzyl ethylenediamine salt | 浙江东盈药业有限公司 | 2023-06-23 | — | — | CN | disclosed |
| US-20230192591-A1 | PROCESS FOR PREPARING TRIENTINE DIHYDROCHLORIDE | COUGHLIN DANIEL J (US) | 2023-06-22 | — | — | US | disclosed |
| CN-109651403-B | Synthesis method of cefoxitin sodium | 上海上药新亚药业有限公司 | 2022-01-07 | — | — | CN | disclosed |
| WO-2021195671-A1 | PROCESS FOR PREPARING TRIENTINE DIHYDROCHLORIDE | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2021-09-30 | — | — | WO | disclosed |
| US-20210238318-A1 | COMPOSITE FUNCTIONAL RESIN, PREPARATION METHOD THEREFOR AND USE THEREOF | NANJING UNIVERSITY & YANCHENG ACADEMY OF ENVIRONMENTAL PROTECTION TECHNOLOGY AND ENGINEERING (CN) | 2021-08-05 | — | — | US | disclosed |
| CN-111217836-A | Preparation method of cefoxitin | 侯二美 | 2020-06-02 | — | — | CN | disclosed |
| US-7071329-B2 | Process for preparing cephalosporins with salified intermediate | ACS DOBFAR S.P.A. (IT) | 2006-07-04 | — | — | US | disclosed |
| US-20050119244-A1 | Process for preparing cephalosporins with salified intermediate | ACS DOBFAR S.P.A. (IT) | 2005-06-02 | — | — | US | disclosed |
| US-20050119478-A1 | Process for preparing cephalosporins with salified intermediate | ACS DOBFAR S.P.A. (IT) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119478-A1 | Process for preparing cephalosporins with salified intermediate | TST, TREH, STS | MEN1 1928/4885KMT2A 3280/4885TDP1 4567/4885 |
| US-20230192591-A1 | PROCESS FOR PREPARING TRIENTINE DIHYDROCHLORIDE | SAMHD1, QDPR, DHPS | MEN1 1968/4885KMT2A 3779/4885TDP1 3410/4885 |
| US-20210238318-A1 | COMPOSITE FUNCTIONAL RESIN, PREPARATION METHOD THEREFOR AND USE THEREOF | ATP5F1C, ATP5MF, ATP5F1B | MEN1 4220/4885KMT2A 3670/4885TDP1 2731/4885 |
| US-20050119244-A1 | Process for preparing cephalosporins with salified intermediate | ACACA, ACACB, COASY | MEN1 2712/4885KMT2A 2014/4885TDP1 3997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.