Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 11/20 | 0.59 |
| ▸ | GRM2 | Q14416 | 9/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL757444 | 0.98 | GRM2 (0.56) | ALOX5GRM2KCNH2 | |
| SCHEMBL756301 | 0.98 | GRM2 (0.56) | ALOX5GRM2KCNH2 | |
| SCHEMBL757882 | 0.94 | ALOX5 (0.66) | ALOX5GRM2KCNH2 | |
| SCHEMBL759460 | 0.94 | ALOX5 (0.66) | ALOX5GRM2KCNH2 | |
| SCHEMBL756291 | 0.90 | GRM2 (0.66) | ALOX5GRM2KCNH2 | |
| SCHEMBL761056 | 0.90 | GRM2 (0.66) | ALOX5GRM2KCNH2 | |
| SCHEMBL755783 | 0.89 | GRM2 (0.67) | ALOX5GRM2KCNH2 | |
| SCHEMBL757893 | 0.89 | GRM2 (0.67) | ALOX5GRM2KCNH2 | |
| SCHEMBL757009 | 0.88 | GRM2 (0.55) | ALOX5GRM2KCNH2 | |
| SCHEMBL756773 | 0.86 | GRM2 (0.66) | ALOX5GRM2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095293-A1 | [1,2,3] TRIAZOLYL SUBSTITUTED COUMARINS AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA LTD. (CA) | 2008-08-14 | — | — | WO | claimed |