⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537926 | 0.92 | — | — | |
| SCHEMBL11289641 | 0.74 | — | — | |
| SCHEMBL104646 | 0.74 | — | — | |
| SCHEMBL2691988 | 0.72 | TRIM24 (0.36) | — | |
| SCHEMBL9175503 | 0.72 | TRIM24 (0.36) | — | |
| SCHEMBL2690369 | 0.72 | TRIM24 (0.36) | — | |
| SCHEMBL9845129 | 0.70 | GRIN1 (0.33) | — | |
| SCHEMBL29554396 | 0.70 | — | — | |
| SCHEMBL8677429 | 0.70 | — | — | |
| SCHEMBL7655453 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1491633-B1 | NOVEL CARBONYL REDUCTASE, GENE ENCODING IT AND PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOLS USING THE SAME | MITSUBISHI CHEM CORP (JP) | 2008-08-27 | — | — | EP | disclosed |
| US-7335757-B2 | Carbonyl reductase, gene encoding the same, and process for producing optically active alcohols using the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2008-02-26 | — | — | US | disclosed |
| US-20050048633-A1 | Novel carbonyl reductase, gene encoding the same, and process for producing optically active alcohols using the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2005-03-03 | — | — | US | disclosed |
| US-4898998-A | BROMINATION; CATALYSIS, CONDENSATION, DEHYDROBROMINATION, BY-PRODUCT INHIBITION | TOYO SODA MANUFACTURING CO., LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| US-4808743-A | Vinyl chloroformates and preparation | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1989-02-28 | — | — | US | disclosed |
| US-4659734-A | BACTERICIDES, FUNGICIDES | NIPPON SHINYAKU CO., LTD. (JP) | 1987-04-21 | — | — | US | disclosed |
| EP-0128465-B1 | PROCESS FOR PRODUCING BROMINATED ACENAPHTHYLENE CONDENSATES | TOSOH CORPORATION (JP) | 1986-08-27 | — | — | EP | disclosed |
| EP-0058392-B1 | SUBSTITUTED CARBOXYLIC ACID DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1985-11-21 | — | — | EP | disclosed |
| EP-0128465-A2 | Process for producing brominated acenaphthylene condensates | TOSOH CORPORATION (JP) | 1984-12-19 | — | — | EP | disclosed |
| EP-0058392-A1 | Substituted carboxylic acid derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1982-08-25 | — | — | EP | disclosed |
| US-4315031-A | Thiosubstituted amino acids | SCIENCE UNION ET CIE (FR) | 1982-02-09 | — | — | US | disclosed |
| EP-0001193-B1 | CARBOCYLIC AMINO ACIDS, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCIENCE UNION ET Cie SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1981-10-14 | — | — | EP | disclosed |
| EP-0001193-A1 | Carbocylic amino acids, methods for their preparation and pharmaceutical compositions containing them | SCIENCE UNION ET Cie SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1979-03-21 | — | — | EP | disclosed |