⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655453 | 1.00 | — | — | |
| SCHEMBL29553061 | 1.00 | — | — | |
| SCHEMBL104646 | 0.74 | — | — | |
| SCHEMBL988034 | 0.74 | — | — | |
| SCHEMBL2690369 | 0.72 | TRIM24 (0.36) | — | |
| SCHEMBL2691988 | 0.72 | TRIM24 (0.36) | — | |
| SCHEMBL9175503 | 0.72 | TRIM24 (0.36) | — | |
| SCHEMBL4969448 | 0.70 | — | — | |
| SCHEMBL9845129 | 0.70 | GRIN1 (0.33) | — | |
| SCHEMBL8677429 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11306107-B2 | Compounds that inhibit MCL-1 protein | AMGEN INC. (US) | 2022-04-19 | — | — | US | disclosed |