Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4311077 | 0.86 | CXCR3 (0.48) | CXCR3KCNH2 | |
| SCHEMBL4310817 | 0.85 | CXCR3 (0.49) | CXCR3KCNH2 | |
| SCHEMBL4316057 | 0.84 | CXCR3 (0.46) | CXCR3KCNH2 | |
| SCHEMBL4969744 | 0.82 | CXCR3 (0.48) | CXCR3KCNH2 | |
| SCHEMBL4318193 | 0.81 | CXCR3 (0.46) | CXCR3KCNH2 | |
| SCHEMBL4307775 | 0.80 | CXCR3 (0.49) | CXCR3KCNH2 | |
| SCHEMBL4982922 | 0.79 | CXCR3 (0.48) | CXCR3KCNH2 | |
| SCHEMBL4309879 | 0.79 | CXCR3 (0.44) | CXCR3KCNH2 | |
| SCHEMBL4315529 | 0.79 | CXCR3 (0.44) | CXCR3KCNH2 | |
| SCHEMBL4309881 | 0.78 | CXCR3 (0.47) | CXCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957076-A2 | THIAZOLE DERIVATIVES AS CXCR3 RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2008-08-20 | — | — | EP | claimed |
| WO-2007064553-A2 | THIAZOLE DERIVATIVES AS CXCR3 RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2007-06-07 | — | — | WO | claimed |