Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84333 | 0.96 | — | — | |
| Iodide SCHEMBL4968720 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL6208613 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL2942851 | 0.93 | — | — | |
| SCHEMBL2124820 | 0.87 | CHRNA7 (0.38) | — | |
| Bromide SCHEMBL29585852 | 0.86 | CHRNA7 (0.33) | — | |
| SCHEMBL24409361 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL2706385 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL3339719 | 0.82 | CHRNA7 (0.35) | — | |
| SCHEMBL2148332 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968980-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES, LTD. (IN) | 2008-09-17 | — | — | EP | claimed |
| WO-2007110782-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-10-04 | — | — | WO | claimed |