Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14387461 | 0.86 | TDP1 (0.57) | TDP1HTTCASP3SENP8SENP7 | |
| SCHEMBL3462835 | 0.84 | TDP1 (1.00) | TDP1HTTMAPTRECQLDUSP3 | |
| SCHEMBL269845 | 0.84 | TDP1 (1.00) | TDP1HTTMAPTRECQLDUSP3 | |
| Ammonia Solution, Strong SCHEMBL10880861 | 0.83 | TDP1 (0.96) | TDP1HTTMAPTRECQLDUSP3 | |
| Hydrochloric Acid SCHEMBL21772081 | 0.83 | TDP1 (0.96) | TDP1HTTMAPTRECQLDUSP3 | |
| SCHEMBL9952228 | 0.77 | HTT (0.56) | TDP1HTTCASP3SENP8SENP7 | |
| Aniline SCHEMBL22169236 | 0.76 | TDP1 (0.82) | TDP1HTTMAPTRECQLDUSP3 | |
| SCHEMBL31735778 | 0.76 | CASP3 (0.57) | TDP1HTTCASP3SENP8SENP7 | |
| SCHEMBL4969195 | 0.75 | MAPT (0.50) | TDP1HTTCASP3SENP8SENP7 | |
| SCHEMBL1629852 | 0.75 | CYP3A4 (0.56) | TDP1HTTCASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980016-B1 | ALIGNING AGENT FOR LIQUID CRYSTAL | NISSAN CHEMICAL IND LTD (JP) | 2008-09-24 | — | — | EP | disclosed |
| US-6274695-B1 | THIN FILM POLYMER | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-08-14 | — | — | US | disclosed |
| EP-0980016-A1 | ALIGNING AGENT FOR LIQUID CRYSTAL | Nissan Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |