Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.59 |
| ▸ | PPARA | Q07869 | 17/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | PPARD | Q03181 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969862 | 1.00 | PPARG (0.59) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL7675427 | 0.86 | PPARG (0.60) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL6157774 | 0.79 | PPARG (0.68) | PPARGPPARAFFAR1 | |
| SCHEMBL4057645 | 0.79 | PPARG (0.68) | PPARGPPARAFFAR1 | |
| SCHEMBL4057652 | 0.79 | PPARG (0.68) | PPARGPPARAFFAR1 | |
| SCHEMBL6158313 | 0.79 | PPARG (0.65) | PPARGPPARAFFAR1 | |
| SCHEMBL6158389 | 0.78 | PPARG (0.72) | PPARGPPARAFFAR1 | |
| SCHEMBL7832391 | 0.78 | PPARG (0.72) | PPARGPPARAFFAR1 | |
| SCHEMBL6158396 | 0.78 | PPARG (0.72) | PPARGPPARAFFAR1 | |
| SCHEMBL7623985 | 0.77 | PPARG (0.55) | PPARGPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962811-A2 | SOLID PREPARATION CONTAINING AN INSULIN SENSITIZER | Takeda Pharmaceutical Company Limited (JP) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007072992-A2 | SOLID PREPARATION CONTAINING AN INSULIN SENSITIZER | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-28 | — | — | WO | disclosed |