Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PTGIR | P43119 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 6/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961889 | 0.81 | HTT (0.51) | HTTMEN1KMT2APTGIRCCR5 | |
| SCHEMBL4961878 | 0.80 | HTT (0.50) | HTTPTGIRACHECCR5CNR2 | |
| SCHEMBL4962835 | 0.78 | HTT (0.60) | HTTMEN1KMT2APTGIRACHE | |
| SCHEMBL4966810 | 0.78 | HTT (0.49) | HTTKMT2ACNR2 | |
| SCHEMBL6414109 | 0.77 | PTGIR (0.50) | MEN1KMT2APTGIRCNR2CNR1 | |
| SCHEMBL6414107 | 0.77 | PTGIR (0.50) | MEN1KMT2APTGIRCNR2CNR1 | |
| SCHEMBL4963023 | 0.76 | HTT (0.54) | HTTCNR2KDM4ELMNAGAA | |
| SCHEMBL4962348 | 0.76 | HTT (0.43) | HTTMEN1KMT2ACNR2LMNA | |
| SCHEMBL4963412 | 0.75 | HTT (0.55) | HTTMEN1KMT2ACNR2KDM4E | |
| SCHEMBL4560442 | 0.75 | HTT (0.63) | HTTMEN1KMT2AACHECCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773780-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-09 | — | — | EP | disclosed |
| EP-1773780-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006012227-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |