Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL216630 | 0.92 | ALDH1A1 (0.40) | ALDH1A1TSHRUSP2HTTSMN1; SMN2 | |
| SCHEMBL212935 | 0.89 | — | — | |
| SCHEMBL11671013 | 0.83 | ALDH1A1 (0.37) | ALDH1A1TSHRUSP2HTTLPAR5 | |
| SCHEMBL11521327 | 0.83 | USP2 (0.39) | TSHRUSP2HTTLPAR5 | |
| SCHEMBL3259045 | 0.78 | — | — | |
| SCHEMBL9117710 | 0.77 | TSHR (0.50) | TSHRUSP2HTTLPAR5 | |
| SCHEMBL21632196 | 0.77 | USP2 (0.48) | ALDH1A1TSHRUSP2HTTSMN1; SMN2 | |
| SCHEMBL22382015 | 0.77 | USP2 (0.39) | ALDH1A1TSHRUSP2HTTLPAR5 | |
| SCHEMBL25996472 | 0.76 | USP2 (0.42) | ALDH1A1TSHRUSP2HTTLPAR5 | |
| SCHEMBL10304916 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957189-A2 | NOVEL DISPERSANT AND COMPOSITIONS THEREOF | Lubrizol Limited (GB) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007111723-A2 | NOVEL DISPERSANT AND COMPOSITIONS THEREOF | LUBRIZOL LIMITED (GB) | 2007-10-04 | — | — | WO | disclosed |