Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3613375 | 0.89 | REN (0.41) | REN | |
| SCHEMBL3613379 | 0.89 | REN (0.41) | REN | |
| SCHEMBL4971952 | 0.89 | REN (0.42) | RENSCN5ASCN9A | |
| SCHEMBL27737826 | 0.89 | REN (0.42) | RENSCN5ASCN9A | |
| SCHEMBL4976075 | 0.89 | REN (0.41) | RENSCN5ASCN9A | |
| SCHEMBL4971136 | 0.85 | REN (0.38) | RENSCN5ASCN9A | |
| SCHEMBL3613911 | 0.81 | REN (0.42) | REN | |
| SCHEMBL3613909 | 0.81 | REN (0.42) | REN | |
| SCHEMBL5515427 | 0.79 | REN (0.65) | REN | |
| SCHEMBL3612250 | 0.78 | STS (0.41) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |