SCHEMBL4970077

SCHEMBL4970077

CCCCCCCC(=O)N(C)Cc1cccc(-c2ccc(CCC(=O)O)cc2F)c1

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.46
PTGS2 P35354 1/20 0.46
FFAR1 O14842 7/20 0.45
FOLH1 Q04609 1/20 0.45
RARB P10826 1/20 0.43
AOC3 Q16853 2/20 0.42
KMT2A Q03164 1/20 0.42
FFAR4 Q5NUL3 2/20 0.41
PLA2G10 O15496 1/20 0.40
PLA2G2A P14555 1/20 0.40
SLCO1B1 Q9Y6L6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4968446 0.89 FFAR1 (0.48) FFAR1FOLH1RARBAOC3KMT2A
SCHEMBL4970065 0.87 FFAR1 (0.46) FFAR1FOLH1AOC3KMT2AFFAR4
SCHEMBL4969532 0.87 FFAR1 (0.44) FFAR1FOLH1AOC3KMT2AFFAR4
SCHEMBL4970418 0.87 FFAR1 (0.42) FFAR1FOLH1AOC3KMT2AFFAR4
SCHEMBL4969426 0.87 FFAR1 (0.50) FFAR1AOC3FFAR4
SCHEMBL4967940 0.86 RXRA (0.47) FFAR1FFAR4
SCHEMBL4969511 0.86 RXRA (0.47) FFAR1AOC3FFAR4
SCHEMBL4969994 0.86 RXRA (0.47) FFAR1FFAR4
SCHEMBL4970598 0.86 AOC3 (0.53) FFAR1AOC3KMT2AFFAR4
SCHEMBL4971031 0.85 FFAR1 (0.42) FFAR1FOLH1AOC3KMT2AFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1781274-B1 NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE RECEPTORS OF PPAR TYPE AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS GALDERMA RES & DEV (FR) 2008-11-05 EP claimed
US-20070207175-A1 Biaromatic compound activators of PPARgamma receptors and cosmetic/pharmaceutical compositions comprised thereof GALDERMA RESEARCH & DEVELOPMENT (FR) 2007-09-06 US claimed
EP-1781274-B1 NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE RECEPTORS OF PPAR TYPE AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS GALDERMA RES & DEV (FR) 2008-11-05 EP disclosed
US-20070207175-A1 Biaromatic compound activators of PPARgamma receptors and cosmetic/pharmaceutical compositions comprised thereof GALDERMA RESEARCH & DEVELOPMENT (FR) 2007-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070207175-A1 Biaromatic compound activators of PPARgamma receptors and cosmetic/pharmaceutical compositions comprised thereof PPARG, PPARA, PPARD FAAH 1231/4885PTGS2 625/4885FFAR1 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.