Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970238 | 1.00 | REN (0.67) | RENCYP3A4 | |
| SCHEMBL4973773 | 0.94 | REN (0.61) | RENCYP3A4 | |
| SCHEMBL4973775 | 0.94 | REN (0.61) | RENCYP3A4 | |
| SCHEMBL4969861 | 0.94 | REN (0.69) | RENCYP3A4 | |
| SCHEMBL4969866 | 0.94 | REN (0.69) | RENCYP3A4 | |
| SCHEMBL4973697 | 0.91 | REN (0.70) | RENCYP3A4 | |
| SCHEMBL4973694 | 0.91 | REN (0.70) | RENCYP3A4 | |
| SCHEMBL2331716 | 0.88 | REN (0.65) | RENCYP3A4 | |
| SCHEMBL2331719 | 0.88 | REN (0.65) | RENCYP3A4 | |
| SCHEMBL2331711 | 0.88 | REN (0.65) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-B1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS INC (US) | 2011-12-21 | — | — | EP | disclosed |
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |