SCHEMBL497029

SCHEMBL497029

c1ccc(OCCCCCCOc2ccccc2)cc1

nearest known ligand 0.94

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 2/20 0.94
HDAC1 Q13547 3/20 0.77
HDAC2 Q92769 3/20 0.77
HDAC3 O15379 1/20 0.77
HDAC4 P56524 1/20 0.77
HDAC7 Q8WUI4 1/20 0.77
HDAC10 Q969S8 1/20 0.77
HDAC11 Q96DB2 1/20 0.77
HDAC8 Q9BY41 1/20 0.77
HDAC6 Q9UBN7 1/20 0.77
HDAC9 Q9UKV0 1/20 0.77
HDAC5 Q9UQL6 1/20 0.77
TAAR1 Q96RJ0 1/20 0.64
ALDH1A1 P00352 1/20 0.64
RECQL P46063 1/20 0.64
DRD2 P14416 1/20 0.62
DRD4 P21917 1/20 0.62
DRD3 P35462 1/20 0.62
LTA4H P09960 2/20 0.61
HTR1B P28222 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10904079 1.00 KCNA3 (0.94) KCNA3HDAC1HDAC2HDAC3HDAC4
SCHEMBL28576557 1.00 KCNA3 (0.94) KCNA3HDAC1HDAC2HDAC3HDAC4
SCHEMBL9011596 1.00 KCNA3 (0.94) KCNA3HDAC1HDAC2HDAC3HDAC4
SCHEMBL28573982 1.00 KCNA3 (0.94) KCNA3HDAC1HDAC2HDAC3HDAC4
SCHEMBL2512157 1.00 KCNA3 (0.94) KCNA3HDAC1HDAC2HDAC3HDAC4
SCHEMBL31229544 1.00 KCNA3 (0.94) KCNA3HDAC1HDAC2HDAC3HDAC4
SCHEMBL9011860 1.00 KCNA3 (0.94) KCNA3HDAC1HDAC2HDAC3HDAC4
SCHEMBL1490164 0.97 KCNA3 (1.00) KCNA3HDAC1HDAC2HDAC3HDAC4
SCHEMBL1025 0.91 KCNA3 (0.88) KCNA3HDAC1HDAC2HDAC3HDAC4
SCHEMBL20530581 0.90 KCNA3 (0.76) KCNA3HDAC1HDAC2HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8034735-B2 Catalyst component for the polymerization of olefins Basell Poliolefine Italia, s.r.l. (IT) 2011-10-11 US claimed
US-20100120998-A1 CATALYST COMPONENT FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2010-05-13 US claimed
CN-117651750-A Ultraviolet absorber, method for producing same, composition, molded article, and coating film 东洋油墨SC控股株式会社 2024-03-05 CN disclosed
US-20240010786-A9 POLYOL COMPOSITIONS PRESIDIUM INNOVATIONS, LLC 2024-01-11 US disclosed
CN-114846085-B Resin composition and molded article 东洋油墨SC控股株式会社 2023-09-08 CN disclosed
CN-113454132-B Ultraviolet-absorbing polymer, molding resin composition, and molded article 东洋油墨SC控股株式会社 2023-05-09 CN disclosed
US-20230127329-A1 LACTONE COMPOUND FUJIFILM CORPORATION (JP) 2023-04-27 US disclosed
CN-116003358-A Lactone compounds 富士胶片株式会社 2023-04-25 CN disclosed
CN-114846085-A Resin composition and molded article 东洋油墨SC控股株式会社 2022-08-02 CN disclosed
US-20210363290-A1 POLYOL COMPOSITIONS PRESIDIUM USA INC (US) 2021-11-25 US disclosed
CN-113454132-A Ultraviolet-absorbing polymer, resin composition for molding, and molded article 东洋油墨SC控股株式会社 2021-09-28 CN disclosed
US-4835133-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-30 US disclosed
US-4833121-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-23 US disclosed
US-4716251-A Diaryloxyalkane bromination process ETHYL CORPORATION (US) 1987-12-29 US disclosed
US-4659643-A A PHENOXY COMPOUND KANZAKI PAPER MANUFACTURING CO. LTD. (JP) 1987-04-21 US disclosed
US-4604404-A Antiviral sulfonated naphthalene formaldehyde condensation polymers A. H. ROBINS COMPANY, INC. (US) 1986-08-05 US disclosed
EP-0105984-A1 Aromatic formaldehyde condensation polymers as dental plaque barriers Johnson & Johnson Products Inc. (US) 1984-04-25 EP disclosed
US-4361547-A PERIODIC APPLICATION TO TEETH JOHNSON & JOHNSON PRODUCTS, INC. (US) 1982-11-30 US disclosed
US-4263223-A Synthesis of 4,4'-dicyano-polyhalo-diphenoxyalkanes LABORATOIRES SEROBIOLOGIQUES S.A. (FR) 1981-04-21 US disclosed
US-4223169-A Process for polybrominating bisphenoxyalkanes FERRO CORPORATION (US) 1980-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230127329-A1 LACTONE COMPOUND LANCL1, GPX1, LOXL1 KCNA3 3210/4885HDAC1 322/4885HDAC2 759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.