Purpurin

Purpurin

SCHEMBL4970376

O=C1c2ccccc2C(=O)c2c(O)c(O)cc(O)c21.O=C1c2ccccc2C(=O)c2ccccc21

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.96
KMT2A Q03164 5/20 0.96
MAPT P10636 4/20 0.96
MAOA P21397 3/20 0.96
HPGD P15428 3/20 0.96
ALDH1A1 P00352 3/20 0.96
MAPK1 P28482 3/20 0.96
TDP1 Q9NUW8 3/20 0.96
KDM4E B2RXH2 2/20 0.96
CYP3A4 P08684 2/20 0.96
ALOX15 P16050 2/20 0.96
ALOX12 P18054 2/20 0.96
RECQL P46063 2/20 0.96
DAPK1 P53355 2/20 0.96
CYP1B1 Q16678 2/20 0.96
HSD17B10 Q99714 2/20 0.96
L3MBTL1 Q9Y468 2/20 0.96
TTR P02766 1/20 0.96
CYP1A1 P04798 1/20 0.96
HSPD1 P10809 1/20 0.96

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Purpurin SCHEMBL29429206 0.98 MEN1 (1.00) MEN1KMT2AMAPTMAOAHPGD
Purpurin SCHEMBL29539242 0.98 MEN1 (1.00) MEN1KMT2AMAPTMAOAHPGD
Purpurin SCHEMBL33871 0.98 MEN1 (1.00) MEN1KMT2AMAPTMAOAHPGD
Purpurin SCHEMBL18840047 0.96 MEN1 (0.96) MEN1KMT2AMAPTMAOAHPGD
Purpurin SCHEMBL9856657 0.96 MEN1 (0.96) MEN1KMT2AMAPTMAOAHPGD
Purpurin SCHEMBL10574533 0.96 MEN1 (0.96) MEN1KMT2AMAPTMAOAHPGD
Purpurin SCHEMBL15205999 0.96 MEN1 (0.96) MEN1KMT2AMAPTMAOAHPGD
Purpurin SCHEMBL2432647 0.91 MEN1 (0.80) MEN1KMT2AMAPTMAOAHPGD
Purpurin SCHEMBL2808530 0.91 MAPT (0.86) MEN1KMT2AMAPTMAOAHPGD
Purpurin SCHEMBL10571410 0.89 MEN1 (0.83) MEN1KMT2AMAPTMAOAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10018622-B2 Methods and kits for differential staining of abnormal urinary system cells ZETIQ TECHNOLOGIES LTD. (IL) 2018-07-10 US disclosed
EP-2643481-B1 METHODS AND KITS FOR DIFFERENTIAL STAINING OF ABNORMAL URINARY SYSTEM CELLS ZETIQ TECHNOLOGIES LTD (IL) 2016-04-27 EP disclosed
US-20150253310-A1 Methods And Kits For Differential Staining Of Abnormal Urinary System Cells ZETIQ TECHNOLOGIES LTD. (IL) 2015-09-10 US disclosed
US-20130266960-A1 Methods And Kits For Differential Staining Of Abnormal Urinary System Cells ZETIQ TECHNOLOGIES LTD. (IL) 2013-10-10 US disclosed
EP-2643481-A1 METHODS AND KITS FOR DIFFERENTIAL STAINING OF ABNORMAL URINARY SYSTEM CELLS Zetiq Technologies Ltd. (IL) 2013-10-02 EP disclosed
WO-2012070041-A1 METHODS AND KITS FOR DIFFERENTIAL STAINING OF ABNORMAL URINARY SYSTEM CELLS ZETIQ TECHNOLOGIES LTD. (IL) 2012-05-31 WO disclosed
EP-1991852-A2 METHODS AND COMPOSITIONS FOR IDENTIFYING A CELL PHENOTYPE Zetiq Technologies Ltd. (IL) 2008-11-19 EP disclosed
WO-2007102146-A2 METHODS AND COMPOSITIONS FOR IDENTIFYING A CELL PHENOTYPE ZETIQ TECHNOLOGIES LTD. (IL) 2007-09-13 WO disclosed