Purpurin

Purpurin

SCHEMBL2808530

COC.O=C1c2ccccc2C(=O)c2c(O)c(O)cc(O)c21

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.86
MEN1 O00255 6/20 0.86
KMT2A Q03164 6/20 0.86
ALDH1A1 P00352 4/20 0.86
MAOA P21397 3/20 0.86
HPGD P15428 3/20 0.86
KDM4E B2RXH2 3/20 0.86
TDP1 Q9NUW8 3/20 0.86
CYP3A4 P08684 2/20 0.86
ALOX15 P16050 2/20 0.86
ALOX12 P18054 2/20 0.86
MAPK1 P28482 2/20 0.86
RECQL P46063 2/20 0.86
DAPK1 P53355 2/20 0.86
CYP1B1 Q16678 2/20 0.86
HSD17B10 Q99714 2/20 0.86
BRCA1 P38398 2/20 0.86
TTR P02766 1/20 0.86
CYP1A1 P04798 1/20 0.86
HSPD1 P10809 1/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Purpurin SCHEMBL29429206 0.93 MEN1 (1.00) MAPTMEN1KMT2AALDH1A1MAOA
Purpurin SCHEMBL29539242 0.93 MEN1 (1.00) MAPTMEN1KMT2AALDH1A1MAOA
Purpurin SCHEMBL33871 0.93 MEN1 (1.00) MAPTMEN1KMT2AALDH1A1MAOA
Purpurin SCHEMBL4970376 0.91 MEN1 (0.96) MAPTMEN1KMT2AALDH1A1MAOA
Purpurin SCHEMBL15205999 0.91 MEN1 (0.96) MAPTMEN1KMT2AALDH1A1MAOA
Purpurin SCHEMBL9856657 0.91 MEN1 (0.96) MAPTMEN1KMT2AALDH1A1MAOA
Purpurin SCHEMBL18840047 0.91 MEN1 (0.96) MAPTMEN1KMT2AALDH1A1MAOA
Purpurin SCHEMBL10574533 0.91 MEN1 (0.96) MAPTMEN1KMT2AALDH1A1MAOA
Purpurin SCHEMBL10571410 0.88 MEN1 (0.83) MAPTMEN1KMT2AALDH1A1MAOA
Purpurin SCHEMBL11811844 0.84 MEN1 (0.83) MAPTMEN1KMT2AALDH1A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES NATURAL EXTRACTION SYS LLC (US) 2026-02-19 US disclosed
US-12409152-B2 Compositions and methods related to dissolved oxides Natural Extraction Systems, LLC (US) 2025-09-09 US disclosed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US disclosed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US disclosed
US-20220362169-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES Natural Extraction Systems, LLC 2022-11-17 US disclosed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO disclosed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO disclosed
WO-2021042001-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES Natural Extraction Systems, LLC (US) 2021-03-04 WO disclosed
US-20100242139-A1 XENOHORMESIS BASED COMPOSITIONS AND METHODS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2010-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB MAPT 3926/4885MEN1 1711/4885KMT2A 4742/4885
US-12409152-B2 Compositions and methods related to dissolved oxides PRKG2, PRKG1, CIT MAPT 2118/4885MEN1 593/4885KMT2A 3932/4885
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES SCO2, CNR2, CNR1 MAPT 3552/4885MEN1 1906/4885KMT2A 4414/4885
US-20220362169-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES PRKG2, PRKG1, CIT MAPT 2118/4885MEN1 593/4885KMT2A 3932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.