Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10517014 | 0.61 | — | — | |
| SCHEMBL10656161 | 0.61 | ALDH1A1 (0.32) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL13698339 | 0.57 | KDM4E (0.44) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL15057332 | 0.56 | — | — | |
| SCHEMBL207506 | 0.54 | KDM4E (0.37) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL30422332 | 0.53 | KDM4E (0.30) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL2162391 | 0.53 | ALDH1A1 (0.36) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL870972 | 0.53 | — | — | |
| SCHEMBL19262448 | 0.52 | KDM4E (0.35) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL1159933 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008132139-A2 | NEW HETEROCYCLIC DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS | UCB PHARMA S.A. (BE) | 2008-11-06 | — | — | WO | disclosed |