Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.72 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4164959 | 0.93 | ACHE (0.73) | ACHEEPHX2EPHX1 | |
| SCHEMBL18426157 | 0.93 | ACHE (0.73) | ACHEEPHX2EPHX1 | |
| SCHEMBL605033 | 0.90 | ACHE (0.69) | ACHEEPHX2EPHX1 | |
| SCHEMBL10939707 | 0.90 | ACHE (0.81) | ACHEEPHX2EPHX1 | |
| SCHEMBL3975468 | 0.90 | ACHE (0.88) | ACHEEPHX2EPHX1 | |
| SCHEMBL7569673 | 0.90 | ACHE (0.81) | ACHEEPHX2EPHX1 | |
| SCHEMBL7693489 | 0.88 | ACHE (0.78) | ACHEEPHX2EPHX1 | |
| SCHEMBL473236 | 0.88 | ACHE (0.85) | ACHEEPHX2EPHX1 | |
| SCHEMBL7785857 | 0.88 | ACHE (0.85) | ACHEEPHX2EPHX1 | |
| SCHEMBL2853012 | 0.88 | ACHE (0.85) | ACHEEPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573887-B2 | Naphthalene derivative | DAITO CHEMIX CORPORATION (JP) | 2017-02-21 | — | — | US | claimed |
| EP-1966159-A2 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007071963-A2 | QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTI-CANCER AGENTS | ASTRAZENECA AB (SE) | 2007-06-28 | — | — | WO | disclosed |