Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970536 | 1.00 | REN (0.50) | RENCYP3A4 | |
| SCHEMBL4968733 | 0.87 | REN (0.56) | RENCYP3A4 | |
| SCHEMBL4968724 | 0.87 | REN (0.56) | RENCYP3A4 | |
| SCHEMBL2325725 | 0.86 | REN (0.51) | RENCYP3A4 | |
| SCHEMBL2325731 | 0.86 | REN (0.51) | RENCYP3A4 | |
| SCHEMBL2325733 | 0.86 | REN (0.51) | RENCYP3A4 | |
| SCHEMBL4981525 | 0.85 | REN (0.51) | RENCYP3A4 | |
| SCHEMBL4981529 | 0.85 | REN (0.51) | RENCYP3A4 | |
| SCHEMBL4974711 | 0.77 | REN (0.43) | RENCYP3A4 | |
| SCHEMBL5599014 | 0.77 | REN (0.57) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |