Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4461975 | 0.76 | MAPK1 (0.40) | TP53TSHRKMT2APSEN1PSEN2 | |
| SCHEMBL3836641 | 0.75 | KMT2A (0.38) | TP53TSHRKMT2APSEN1PSEN2 | |
| SCHEMBL28284568 | 0.75 | KMT2A (0.38) | TP53TSHRKMT2APSEN1PSEN2 | |
| SCHEMBL7704576 | 0.73 | MAPT (0.38) | TP53TSHRKMT2ANPC1RAB9A | |
| SCHEMBL2344726 | 0.71 | KMT2A (0.38) | TP53TSHRKMT2APSEN1PSEN2 | |
| SCHEMBL27772509 | 0.70 | — | — | |
| SCHEMBL27746516 | 0.69 | MAPT (0.36) | TP53TSHRKMT2ANPC1RAB9A | |
| SCHEMBL11285913 | 0.69 | MAPT (0.36) | TP53TSHRKMT2APSEN1PSEN2 | |
| SCHEMBL28260453 | 0.68 | KMT2A (0.32) | TP53TSHRKMT2AMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28776637 | 0.68 | MAPT (0.35) | TP53TSHRKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971618-A2 | MODULATORS OF HYPOXIA INDUCIBLE FACTOR-1 AND RELATED USES | BTG INTERNATIONAL LIMITED (GB) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007081835-A2 | MODULATORS OF HYPOXIA INDUCIBLE FACTOR-1 AND RELATED USES | BTG INTERNATIONAL LIMITED (GB) | 2007-07-19 | — | — | WO | disclosed |