Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28113438 | 0.84 | HTT (0.32) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL28112857 | 0.84 | HTT (0.32) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL28112847 | 0.81 | CYP1A2 (0.31) | — | |
| SCHEMBL11285913 | 0.81 | MAPT (0.36) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27746516 | 0.81 | MAPT (0.36) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18952939 | 0.81 | L3MBTL1 (0.34) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL28776637 | 0.80 | MAPT (0.35) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28836804 | 0.79 | L3MBTL1 (0.35) | ALDH1A1RAB9ATSHR | |
| SCHEMBL11463510 | 0.78 | KMT2A (0.35) | MAPTALDH1A1SMN1; SMN2KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL7356841 | 0.77 | MEN1 (0.34) | MAPTALDH1A1SMN1; SMN2KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6361940-B1 | IMMOBILIZATION; GENETIC ENGINEERING | QIAGEN GENOMICS, INC. | 2002-03-26 | — | — | US | disclosed |