Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28947682 | 0.91 | ALDH1A1 (0.53) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL5438921 | 0.86 | NPC1 (0.67) | ALDH1A1MEN1CASP1KMT2ACYP1A2 | |
| SCHEMBL3726615 | 0.81 | NPC1 (0.68) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL29485612 | 0.81 | NPC1 (0.68) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL28192579 | 0.77 | NPC1 (0.74) | ALDH1A1MEN1CASP1KMT2ACYP1A2 | |
| SCHEMBL23441982 | 0.74 | NPC1 (0.64) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL7905481 | 0.74 | NPC1 (0.84) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL6005419 | 0.74 | NPC1 (0.59) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL12075052 | 0.74 | NPC1 (0.59) | ALDH1A1MEN1CASP1CASP7KMT2A | |
| SCHEMBL19506133 | 0.74 | NPC1 (0.64) | ALDH1A1MEN1CASP1CASP7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1969051-A2 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | N.V. Organon (NL) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007079180-A2 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | N.V. ORGANON (NL) | 2007-07-12 | — | — | WO | disclosed |