Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17708716 | 0.84 | CYP19A1 (0.49) | CYP19A1LMNAMAPTALOX12SMN1; SMN2 | |
| SCHEMBL4359940 | 0.80 | CYP19A1 (0.49) | CYP19A1LMNAMAPTALOX12SMN1; SMN2 | |
| SCHEMBL29066383 | 0.79 | CYP19A1 (0.51) | CYP19A1 | |
| SCHEMBL20594070 | 0.79 | CYP19A1 (0.51) | CYP19A1 | |
| SCHEMBL20594068 | 0.79 | CYP19A1 (0.51) | CYP19A1 | |
| SCHEMBL16160573 | 0.76 | ESR2 (0.63) | CYP19A1LMNA | |
| SCHEMBL30362997 | 0.75 | MEN1 (0.48) | MEN1KMT2ATDP1 | |
| SCHEMBL17709139 | 0.75 | CYP19A1 (0.82) | CYP19A1 | |
| SCHEMBL17709142 | 0.75 | CYP19A1 (0.82) | CYP19A1 | |
| SCHEMBL4360502 | 0.73 | ESR1 (0.63) | CYP19A1LMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809618-A4 | CHROMAN DERIVATIVES, MEDICAMENTS AND USE IN THERAPY | NOVOGEN RES PTY LTD (AU) | 2008-11-19 | — | — | EP | claimed |
| EP-1809618-A1 | CHROMAN DERIVATIVES, MEDICAMENTS AND USE IN THERAPY | Novogen Research Pty Ltd (AU) | 2007-07-25 | — | — | EP | claimed |
| WO-2006032086-A1 | CHROMAN DERIVATIVES, MEDICAMENTS AND USE IN THERAPY | NOVOGEN RESEARCH PTY LTD (AU) | 2006-03-30 | — | — | WO | claimed |