Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4972000 | 0.75 | CYP19A1 (0.54) | MEN1KMT2ATDP1 | |
| SCHEMBL18898168 | 0.73 | MEN1 (0.49) | MEN1KMT2AESR1ESR2 | |
| SCHEMBL2719223 | 0.73 | MEN1 (0.49) | MEN1KMT2AESR1ESR2 | |
| SCHEMBL15312297 | 0.73 | MEN1 (0.49) | MEN1KMT2AESR1ESR2 | |
| SCHEMBL30362919 | 0.73 | MEN1 (0.49) | MEN1KMT2AESR1ESR2 | |
| SCHEMBL10073997 | 0.73 | MEN1 (0.49) | MEN1KMT2AESR1ESR2 | |
| SCHEMBL4973196 | 0.73 | PLA2G10 (0.48) | PLA2G10PLA2G2APLA2G5ESR1ESR2 | |
| SCHEMBL30362939 | 0.72 | MEN1 (0.44) | MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL30517758 | 0.72 | MEN1 (0.44) | MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL8501518 | 0.71 | ESR1 (0.56) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4164632-A1 | COMBINATION THERAPIES | MEI Pharma, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |