Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3479799 | 0.92 | KMT2A (0.53) | ALDH1A1GAAKMT2ALMNAPOLB | |
| SCHEMBL3479879 | 0.87 | MAPK9 (0.55) | ALDH1A1KMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL2421336 | 0.84 | MAPK9 (0.55) | ALDH1A1GAAKMT2ALMNASMN1; SMN2 | |
| SCHEMBL7434456 | 0.82 | KMT2A (0.48) | ALDH1A1GAAKMT2ALMNAPOLB | |
| SCHEMBL4197141 | 0.81 | KMT2A (0.40) | ALDH1A1GAAKMT2ALMNASMN1; SMN2 | |
| SCHEMBL2428799 | 0.78 | MAPK9 (0.61) | ALDH1A1KMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL2422063 | 0.77 | MAPK9 (0.52) | ALDH1A1GAAKMT2ALMNASMN1; SMN2 | |
| SCHEMBL2428926 | 0.77 | MAPK9 (0.53) | ALDH1A1GAAKMT2ALMNAPOLB | |
| SCHEMBL2419998 | 0.77 | MAPK9 (0.53) | ALDH1A1GAAKMT2ALMNAPOLB | |
| SCHEMBL2423789 | 0.76 | MAPK9 (0.56) | ALDH1A1KMT2ALMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904181-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011762-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2007-01-25 | — | — | WO | disclosed |