Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3479799 | 0.90 | KMT2A (0.53) | KMT2AMAPK9MAPK10SMN1; SMN2LMNA | |
| SCHEMBL3480233 | 0.89 | MAPK9 (0.55) | KMT2AMAPK9MAPK10LMNAALDH1A1 | |
| SCHEMBL2421336 | 0.84 | MAPK9 (0.55) | KMT2AMAPK9MAPK10SMN1; SMN2LMNA | |
| SCHEMBL4197141 | 0.83 | KMT2A (0.40) | KMT2AMAPK9MAPK10SMN1; SMN2LMNA | |
| SCHEMBL4972021 | 0.82 | ALDH1A1 (0.47) | KMT2AMAPK9MAPK10SMN1; SMN2LMNA | |
| SCHEMBL2419827 | 0.81 | MAPK9 (0.57) | KMT2AMAPK9MAPK10SMN1; SMN2LMNA | |
| SCHEMBL2423386 | 0.77 | MAPT (0.60) | KMT2AMAPK9MAPK10SMN1; SMN2LMNA | |
| SCHEMBL3480063 | 0.77 | MAPK9 (0.51) | KMT2AMAPK9MAPK10SMN1; SMN2LMNA | |
| SCHEMBL2425741 | 0.76 | MAPK9 (0.59) | KMT2AMAPK9MAPK10SMN1; SMN2LMNA | |
| SCHEMBL2418948 | 0.76 | MAPK9 (0.59) | KMT2AMAPK9MAPK10SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | claimed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | claimed |