Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.51 |
| ▸ | OGA | O60502 | 5/20 | 0.49 |
| ▸ | CDK2 | P24941 | 7/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.48 |
| ▸ | CDK4 | P11802 | 3/20 | 0.48 |
| ▸ | CDK1 | P06493 | 2/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.47 |
| ▸ | CCND1 | P24385 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL233711 | 0.84 | CDK2 (0.60) | LMNAMAPTMEN1KMT2AAOC3 | |
| SCHEMBL12523827 | 0.84 | LMNA (0.55) | LMNAMAPTMEN1KMT2AAOC3 | |
| SCHEMBL4963441 | 0.83 | LMNA (0.53) | LMNAMAPTMEN1KMT2AAOC3 | |
| SCHEMBL16113800 | 0.83 | LMNA (0.57) | LMNAMAPTMEN1KMT2AAOC3 | |
| SCHEMBL18135139 | 0.81 | CDK2 (0.64) | LMNAMAPTMEN1KMT2AAOC3 | |
| SCHEMBL31128699 | 0.81 | LMNA (0.52) | LMNAMAPTMEN1KMT2AAOC3 | |
| SCHEMBL21358854 | 0.81 | LMNA (0.52) | LMNAMAPTMEN1KMT2AAOC3 | |
| SCHEMBL7992945 | 0.81 | CCNE1 (0.48) | LMNAMAPTMEN1KMT2AAOC3 | |
| SCHEMBL21359490 | 0.80 | AOC3 (0.55) | LMNAMAPTMEN1KMT2AAOC3 | |
| SCHEMBL21770026 | 0.80 | CDK2 (0.53) | LMNAMAPTMEN1KMT2AAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888546-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006125805-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2006-11-30 | — | — | WO | disclosed |