Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752805 | 0.90 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL4973787 | 0.90 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL4974662 | 0.89 | CA12 (0.33) | — | |
| SCHEMBL4972570 | 0.89 | CA12 (0.33) | — | |
| SCHEMBL14910149 | 0.80 | EPHX2 (0.40) | — | |
| SCHEMBL16164720 | 0.80 | EPHX2 (0.40) | — | |
| SCHEMBL15399305 | 0.80 | EPHX2 (0.40) | — | |
| SCHEMBL1439228 | 0.80 | EPHX2 (0.40) | — | |
| SCHEMBL14910147 | 0.80 | EPHX2 (0.40) | — | |
| SCHEMBL15562277 | 0.77 | CA12 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |