⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5553224 | 0.69 | — | — | |
| SCHEMBL29522058 | 0.69 | — | — | |
| SCHEMBL497217 | 0.67 | NOTUM (0.44) | — | |
| SCHEMBL967548 | 0.63 | PDPK1 (0.38) | — | |
| SCHEMBL19435586 | 0.61 | CLK4 (0.38) | — | |
| SCHEMBL17802320 | 0.59 | — | — | |
| SCHEMBL969568 | 0.58 | — | — | |
| SCHEMBL7000232 | 0.58 | — | — | |
| SCHEMBL11349616 | 0.58 | — | — | |
| SCHEMBL21315699 | 0.58 | L3MBTL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7855212-B2 | Pyridinyl acetonitriles | MERCK SERONO SA (CH) | 2010-12-21 | — | — | US | claimed |
| EP-1320526-B1 | PHARMACEUTICALLY ACTIVE BENZSULFONAMIDE DERIVATIVES AS INHIBITORS OF PROTEIN JUNKINASES | MERCK SERONO SA (CH) | 2010-08-18 | — | — | EP | claimed |
| EP-1399156-A2 | ALKYLIDENE PIRAZOLIDINEDIONE DERIVATIVES AND THEIR USE FOR TREATING DIABETES AND OBESITY | Applied Research Systems ARS Holding N.V. (AN) | 2004-03-24 | — | — | EP | claimed |
| WO-2002102359-A2 | ALKYLIDENE PYRAZOLIDINEDIONE DERIVATIVES AND USE FOR TREATING DIABETES AND OBESITY | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2002-12-27 | — | — | WO | claimed |
| WO-2024074436-A1 | LACTATE ENHANCING COMPOUNDS AND USES THEREOF | GLIAPHARM SA (CH) | 2024-04-11 | — | — | WO | disclosed |
| EP-4077308-B1 | ANTI-MALARIAL AGENTS | UNIV TEXAS (US) | 2024-02-14 | — | — | EP | disclosed |
| US-20230372306-A1 | COMPOSITIONS AND METHODS FOR DELAYING THE INCIDENCE OF LABOR | XOMA (US) LLC | 2023-11-23 | — | — | US | disclosed |
| US-20230277501-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY | 2023-09-07 | — | — | US | disclosed |
| EP-4132918-A1 | NEW ANTI-MALARIAL AGENTS | University Of Kentucky Research Foundation (US) | 2023-02-15 | — | — | EP | disclosed |
| EP-3892332-A1 | NEW ANTI-MALARIAL AGENTS | University Of Kentucky Research Foundation (US) | 2021-10-13 | — | — | EP | disclosed |
| WO-2021191412-A1 | CATHEPSIN SUBSTRATES & CATHEPSIN INHIBITORS AND USES THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2021-09-30 | — | — | WO | disclosed |
| EP-3884948-A1 | CATHEPSIN INHIBITORS AND USES THEREOF | Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) | 2021-09-29 | — | — | EP | disclosed |
| WO-2001029028-A1 | 9- (PIPERAZINYLALKYL) CARBAZOLES AS BAX-MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-26 | — | — | WO | disclosed |
| EP-1094063-A1 | 9-(Piperazinylalkyl)carbazoles as Bax-modulators | Applied Research Systems ARS Holding N.V. (AN) | 2001-04-25 | — | — | EP | disclosed |
| WO-2001023379-A1 | PHARMACEUTICALLY ACTIVE SULFONYL AMINO ACID DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | disclosed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | disclosed |
| WO-2001023382-A1 | PHARMACEUTICALLY ACTIVE SULFONYL HYDRAZIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | disclosed |
| EP-1088822-A1 | Pharmaceutically active sulfonyl hydrazide derivatives | Applied Research Systems ARS Holding N.V. (AN) | 2001-04-04 | — | — | EP | disclosed |
| EP-1088821-A1 | Pharmaceutically active sulfonamide derivatives | Applied Research Systems ARS Holding N.V. (AN) | 2001-04-04 | — | — | EP | disclosed |
| EP-1088815-A1 | Pharmaceutically active sulfonyl amino acid derivatives | Applied Research Systems ARS Holding N.V. (AN) | 2001-04-04 | — | — | EP | disclosed |