Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | STK4 | Q13043 | 1/20 | 0.31 |
| ▸ | STK3 | Q13188 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4972260 | 0.89 | — | — | |
| SCHEMBL4972475 | 0.84 | CNR2 (0.31) | SMN1; SMN2STK4STK3 | |
| SCHEMBL4974698 | 0.77 | SMN1; SMN2 (0.35) | SMN1; SMN2STK4STK3PTPN11 | |
| SCHEMBL4974375 | 0.73 | JAK2 (0.36) | — | |
| SCHEMBL1190693 | 0.70 | KHK (0.38) | — | |
| SCHEMBL4972492 | 0.68 | JAK2 (0.36) | STK4STK3 | |
| SCHEMBL29235112 | 0.67 | SMN1; SMN2 (0.37) | SMN1; SMN2STK4STK3PTPN11 | |
| SCHEMBL5011620 | 0.65 | ABL1 (0.41) | SMN1; SMN2 | |
| SCHEMBL31451512 | 0.64 | KHK (0.33) | — | |
| SCHEMBL30741898 | 0.62 | PTPN11 (0.36) | SMN1; SMN2STK4STK3PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008132502-A1 | PYRAZOLYL-AMINO-SUBSTITUTED PYRIMIDINES AND THEIR USE FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2008-11-06 | — | — | WO | disclosed |