Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4985706 | 0.84 | JAK2 (0.58) | JAK2JAK3 | |
| SCHEMBL4974705 | 0.84 | JAK2 (0.49) | JAK2JAK3 | |
| SCHEMBL4971410 | 0.80 | JAK2 (0.36) | JAK2JAK3 | |
| SCHEMBL4978667 | 0.79 | JAK3 (0.62) | JAK2JAK3 | |
| SCHEMBL4972492 | 0.77 | JAK2 (0.36) | JAK2JAK3 | |
| SCHEMBL4972260 | 0.77 | — | — | |
| SCHEMBL4972541 | 0.74 | JAK2 (0.46) | JAK2JAK3 | |
| SCHEMBL4972192 | 0.73 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL4974714 | 0.73 | JAK2 (0.47) | JAK2JAK3 | |
| SCHEMBL4972475 | 0.72 | CNR2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008132502-A1 | PYRAZOLYL-AMINO-SUBSTITUTED PYRIMIDINES AND THEIR USE FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2008-11-06 | — | — | WO | disclosed |