Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.60 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4972259 | 1.00 | TP53 (0.68) | TP53HTTAKR1C3AKR1C1MEN1 | |
| SCHEMBL39098 | 0.95 | TP53 (0.75) | TP53HTTAKR1C3AKR1C1MEN1 | |
| SCHEMBL29898330 | 0.95 | TP53 (0.75) | TP53HTTAKR1C3AKR1C1MEN1 | |
| SCHEMBL7277760 | 0.90 | TP53 (0.63) | TP53HTTAKR1C3AKR1C1MEN1 | |
| SCHEMBL7277756 | 0.90 | TP53 (0.63) | TP53HTTAKR1C3AKR1C1MEN1 | |
| SCHEMBL4793304 | 0.88 | TP53 (0.61) | TP53HTTAKR1C3AKR1C1MEN1 | |
| SCHEMBL13860589 | 0.88 | TP53 (0.67) | TP53HTTAKR1C3AKR1C1MEN1 | |
| SCHEMBL21051764 | 0.88 | TP53 (0.61) | TP53HTTAKR1C3AKR1C1MEN1 | |
| SCHEMBL4793303 | 0.88 | TP53 (0.61) | TP53HTTAKR1C3AKR1C1MEN1 | |
| SCHEMBL15484230 | 0.86 | TP53 (0.59) | TP53HTTAKR1C3AKR1C1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1990332-A1 | NAPHTHACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | Idemitsu Kosan Co., Ltd. (JP) | 2008-11-12 | — | — | EP | disclosed |
| US-20070222373-A1 | NAPHTHACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-5639789-A | ANTITHROMBOTIC DRUGS | TANABE SEIYAKU CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0563798-B1 | Butadiene derivatives, their preparation and use as an antithrombotic agent | TANABE SEIYAKU CO (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5514815-A | ANTITHROMBOTIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0563798-A1 | Butadiene derivatives, their preparation and use as an antithrombotic agent | TANABE SEIYAKU CO., LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070222373-A1 | NAPHTHACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | ENDOD1, ENO1, CELA1 | TP53 2572/4885HTT 3780/4885AKR1C3 3115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.